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SFN Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P31947, O70456 |
| Other Accession | Q0VC36, NP_006133.1, O77642, P31947, O70456 |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Antigen Region | 120-149 aa |
| Other Names | 14-3-3 protein sigma, Epithelial cell marker protein 1, Stratifin, SFN, HME1 |
|---|---|
| Target/Specificity | This SFN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the Central region of human SFN. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SFN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.
References
Ren, H.Z., et al. Dig. Dis. Sci. 55(9):2552-2560(2010)
Liu, Y., et al. Brain Res. 1336, 98-102 (2010) :
Pei, H.P., et al. Zhonghua Wei Chang Wai Ke Za Zhi 13(3):213-215(2010)
Syrjanen, S., et al. Am. J. Clin. Pathol. 133(2):232-240(2010)
Zurita, M., et al. BMC Cancer 10, 217 (2010) :
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